Publications

Mass Spectrometry and Proteomics Facility (MSPF)

Selected publications

  1. Zhang, S., Owyong, T. C., Sanislav, O., Englmaier, L., Sui, X., Wang, G. et al. (2025) Global analysis of endogenous protein disorder in cells Nat Methods 22, 124-134 10.1038/s41592-024-02507-z
  2. Spencer, G. W. K., Li, X., Lam, K. W. L., Mutch, G., Fry, F. H., andGras, S. L. (2025) Codeine 3-O-demethylase catalyzed biotransformation of morphinan alkaloids in Escherichia coli: site directed mutagenesis of terminal residues improves enzyme expression, stability and biotransformation yield J Biol Eng 19, 9 10.1186/s13036-025-00477-0
  3. Li, J. G., Bowen, C. J., Chan, B., Takahashi, H., andO'Hair, R. A. J. (2025) Tandem Mass Spectrometry of Perfluorocarboxylate Anions: Fragmentation Induced by Reactive Species Formed From Microwave Excited Hydrogen and Water Plasmas Rapid Commun Mass Spectrom 39, e9953 10.1002/rcm.9953
  4. Ziegler, A. R., Dufour, A., Scott, N. E., andEdgington-Mitchell, L. E. (2024) Ion Mobility-Based Enrichment-Free N-Terminomics Analysis Reveals Novel Legumain Substrates in Murine Spleen Mol Cell Proteomics 23, 100714 10.1016/j.mcpro.2024.100714
  5. Xie, S. C., Wang, Y., Morton, C. J., Metcalfe, R. D., Dogovski, C., Pasaje, C. F. A. et al. (2024) Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase Nat Commun 15, 937 10.1038/s41467-024-45224-z
  6. Turner, A. M., Li, L., Monk, I. R., Lee, J. Y. H., Ingle, D. J., Portelli, S. et al. (2024) Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin Nature 635, 969-977 10.1038/s41586-024-08095-4
  7. Massey, S., Ang, C. S., Davidson, N. M., Quigley, A., Rollo, B., Harris, A. R. et al. (2024) Novel CDKL5 targets identified in human iPSC-derived neurons Cell Mol Life Sci 81, 347 10.1007/s00018-024-05389-8
  8. Jia, X., Crawford, J. C., Gebregzabher, D., Monson, E. A., Mettelman, R. C., Wan, Y. et al. (2024) High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases Cell 187, 4586-4604 e4520 10.1016/j.cell.2024.07.026
  9. Crameri, J. J., Palmer, C. S., Stait, T., Jackson, T. D., Lynch, M., Sinclair, A. et al. (2024) Reduced Protein Import via TIM23 SORT Drives Disease Pathology in TIMM50-Associated Mitochondrial Disease Mol Cell Biol 44, 226-244 10.1080/10985549.2024.2353652
  10. Simon, P. M., Castillo, J. O., Owyong, T. C., White, J. M., Saker Neto, N., andWong, W. W. H. (2023) Protection of Boronic Acids Using a Tridentate Aminophenol ONO Ligand for Selective Suzuki-Miyaura Coupling J Org Chem 88, 1590-1599 10.1021/acs.joc.2c02651
  11. Sethi, A., Rawlinson, S. M., Dubey, A., Ang, C. S., Choi, Y. H., Yan, F. et al. (2023) Structural insights into the multifunctionality of rabies virus P3 protein Proc Natl Acad Sci U S A 120, e2217066120 10.1073/pnas.2217066120
  12. Palmieri, M., Catimel, B., Mouradov, D., Sakthianandeswaren, A., Kapp, E., Ang, C. S. et al. (2023) PI3K-alpha translocation mediates nuclear PtdIns(3,4,5)P(3) effector signaling in colorectal cancer Mol Cell Proteomics 100529 10.1016/j.mcpro.2023.100529
  13. Lau, M. J., Nie, S., Yang, Q., Harshman, L. G., Mao, C., Williamson, N. A. et al. (2023) Lipidomic Profiling Reveals Concerted Temporal Patterns of Functionally Related Lipids in Aedes aegypti Females Following Blood Feeding Metabolites 13, 10.3390/metabo13030421
  14. Ameen, S. S., Griem-Krey, N., Dufour, A., Hossain, M. I., Hoque, A., Sturgeon, S. et al. (2023) N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection Mol Cell Proteomics 22, 100543 10.1016/j.mcpro.2023.100543
  15. Xie, S. C., Metcalfe, R. D., Dunn, E., Morton, C. J., Huang, S. C., Puhalovich, T. et al. (2022) Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy Science 376, 1074-1079 10.1126/science.abn0611