Star-shaped polypeptides

minute read

Pink drug-resistant Neisseria gonorrhoeae bacteria on a blue background

Multi-drug resistant (MDR) bacteria are a threat to human health. Image: Medical illustration of drug-resistant, Neisseria gonorrhoeae bacteria.

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The technology

University of Melbourne researchers have created star-shaped polypeptides. These are Structurally Nanoengineered Antimicrobial Peptide Polymers, or SNAPPs. They have anti-bacterial properties, including against MDR bacteria.

SNAPPs also have adjuvant activity, improving the efficiency of existing antibiotics.

Market need

Multi-drug resistant (MDR) bacteria are a threat to human health. The development of novel anti-bacterial therapies is a global health priority.

Technology status

Proof-of-concept has been achieved using various in vitro microscopy and bioassay studies. These show SNAPPs’ antimicrobial activity, mode of action and low toxicity.

Contact

Shereen Tan

Tan.s@unimelb.edu.au

Phone +61 3 9035 6020


Star-shaped Polypeptides flyer (PDF)

Image by Medical Illustrator Alissa Eckert. Photo by US Centers for Disease Control and Prevention (CDC) on Unsplash.