Medical Research Future Fund

The Medical Research Future Fund (MRFF) is a $20 billion vehicle for investment in health and medical research. It represents the single largest boost to research funding in Australia’s history. It will support research and innovation activities with the objective of improving the health and wellbeing of Australians.

  • What is the MRFF?

    Established under the Medical Research Future Fund Act 2015, the MRFF is a $20 billion investment by the Government to support, transform, and drive cutting-edge medical research and innovation in Australia.

    Strategic and priority areas for the fund are guided by an Advisory Board, who developed the 5-year Strategy (2016–2021) which outline the framework for the MRFF as six strategic platforms:

    1. Strategic and international horizons
    2. Data and infrastructure
    3. Health services and systems
    4. Capacity and collaborations
    5. Trials and translation
    6. Commercialisation

    The Strategy determines the biennial Priorities (2016 - 2018).

    Some funding disbursements are expected to be made through competitive grants processes and targeted calls administered by the Department of Health, NHMRC, or other independent bodies.

    MRFF Factsheet

  • 2018 Federal Budget Update

    In the 2018 Federal Budget, the Government announced $1.3 billion towards the National Health and Medical Industry Growth Plan, including investments from the MRFF:

    • $240 million committed to a Frontier Health and Medical Research program
    • $248 million for rare cancers and rare diseases clinical trials
    • $32 million for industry research collaborations
    • $125 million to establish a Targeted Translation Research Accelerator for chronic disease
    • $62.3 million for biomedical and medical technology programs.
    • $125 million for a Million Minds Mental Health Mission
    • $150 million for translation of research into better patient outcomes

    For summaries of each investment, please refer to the Department of Health webpage.

    These investments are expected to lead to funding opportunities in the near future however the mechanism for which is currently unknown.

    Any funding opportunities derived from these investments will be advertised on this page and Research Professional as soon as information becomes available.

    Other useful information is available in Research Australia's Budget Analysis Summary.

  • Current Funding Opportunities

    2018 MRFF - Biomedical Translation Bridge

    Key Dates:

    Friday 13 July 2018 – Opportunity published on Grant Connect

    5pm AEST Tuesday 21 August 2018 – Submission deadline.

    Funding Documents - The CI should read the MRFF BTB Grant Guidelines and Fund Factsheet respectively. These documents can be found on the Grant Connect website GO ID GO1438.


    The BTB grant opportunity will provide up to $22.3 million over four years to support eligible organisations to fund and nurture eligible early stage health and medical research ventures to reach proof of concept stage.

    Proposed projects are expected to put in place systems to enable service functions including:

    • selecting, providing funding to, and managing a portfolio of ventures
    • providing mentoring and networking capabilities to aid in the development of these ventures, including helping to establish development milestones that are commercially relevant
    • soliciting and securing relevant and appropriate philanthropic donations and third-party sponsorship or co-investment and then provide this to the selected ventures to aid in their development
    • selecting successful ventures, through an open and competitive selection process, with possible subsequent intake rounds or a continuous intake process
    • establishing a suitably qualified selection panel, in consultation with the department and the Department of Health, that will be used to select ventures to be funded
    • executing and managing contractual arrangements with the selected ventures (between $200,000 and $1 million with a maximum duration of three years) including terminating funding and support for ventures that fail to progress

    Eligible applications will be assessed based on merit against the following two criteria (refer to section 6 of the BTB Grant Guidelines):

    • Benefits of your project
    • Your capacity, capability and resources to manage the project

    Applications can be submitted directly via the Online Application Form by the 5pm AEST Tuesday, 21 August 2018.

    Please lodge your application on the Themis Grant Submission Workbench after you have submitted your application directly via the online portal.

    Contact: Ken Choong,, 9035 8763

    2019 MRFF – Rare Cancers, Rare Diseases and Unmet Need

    Key Dates:

    Monday 25 June 2018 – Application Open in RGMS
    Monday 30 July 2018 – Applications seeking internal review should be emailed to RIC
    Wednesday 1 August 2018 – NHMRC Minimum Data deadline. Applications not completing minimum data will not be allowed to proceed further.
    10am AEST Monday 13 August 2018 – Final submissions due to RIC. CIA to submit a fully completed UoM Authority to Submit Form to RIC and certify the application in RGMS.

    Submit a Notice of Intent (NOI) – The NOI should be completed early and provided to RIC with CIA contact details.

    Funding Documents – The CI should read the NHMRC - MRFF RCRDUN Grant Guidelines and Category Descriptors respectively. These documents can be found on the Grant Connect website GO ID GO1375.

    Please note: Our advice from NHMRC/MRFF, infers that “unmet need” includes any health condition with limited effective treatment options. Rare cancers and rare diseases are specific, life threatening or chronically debilitating health conditions that affect fewer than 1 in 2,000 people in the population.

    The Australian Government has announced a total of up to $33 million from the MRFF for this grant opportunity. It is anticipated that up to twenty grants of up to five years duration will be considered with funding anticipated to commence in January 2019. This competitive grant opportunity will provide support for publicly funded clinical trials that address areas of health burden and unmet need, such as rare cancers and rare diseases. Applications to this grant opportunity must propose a clinical trial that addresses an ‘unmet medical need’ by improving the health outcomes for members of the Australian community living with serious health conditions whose diagnosis or treatment is not adequately addressed by existing options. The grant opportunity incorporates a call for applications to the Australian Brain Cancer Mission.

    Rare cancers and rare diseases are specific, life threatening or chronically debilitating health conditions that affect fewer than 1 in 2,000 people in the population1. There are limited effective treatment options for many rare cancers and diseases, and the combined health burden is significant. The grant opportunity aims to increase clinical trial activity in Australia by supporting new, high quality research. Novel and innovative clinical trial methodologies are encouraged, such as the application of precision medicine to take individual genetic variation into account in disease treatment. Applications proposing participation in international multi-centre clinical trials or utilising the capabilities of established clinical quality registries are also encouraged.

    Brain cancer is the sixth leading cause of cancer burden and brain cancers carry high rates of morbidity and mortality. The young are disproportionately affected by brain cancer, being the leading cause of cancer-related deaths for those under 25 years of age. The objective of this grant opportunity through the Mission is to support increased and equitable access and participation in clinical trials for people with brain cancer. Specifically through this funding, the Australian Brain Cancer Mission is seeking to fund new or expanded innovative clinical trials in brain cancer that could involve international collaborations.
    The clinical trials should:
    *be for children, adolescents and young adults, or adults with malignant brain cancer* and
    *support increased and equitable access and participation.
    The clinical trials may be in areas of:
    *Treatment - Discovery and Development, or Clinical Application of Localized Therapies, Systemic Therapies, or Combinations of Localised and Systemic Therapies, including the assessment of new biological end points.
    *Cancer Control, Survivorship & Outcomes - Patient Care, Survivorship, or End-of-Life Care

    Contact: Ken Choong,, 9035 8763

    MRFF Frontier Health and Medical Research program

    Background information to support new proposal development

    Background: The Medical Research Future Fund (MRFF) is a substantial new source of funding provided by the Federal Department of Health. Its aim is to support the innovative world-class research that will improve human health. A range of new schemes have recently been announced as part of the 2018-2019 Federal budget.

    One of the new schemes is the Frontier Health and Medical Research program. This program will provide over $240 million to researchers and their collaborators over five years to support innovative ’out-of-the-box’ ideas and discoveries. It aims to unlock groundbreaking research which provides new treatments and technologies to improve health and open new markets for industry growth.

    Process: The Frontier Health and Medical Research program will operate under a two-stage process:

    Stage 1 Involves an open competitive expression of interest
    Researchers must articulate their idea and its merit; demonstrate its novelty, competitiveness and transformative nature, and its potential for partnerships
    Successful stage 1 applicants will receive $1 million and have approximately 1 year to advance their idea and develop a business case to put forward for potential stage 2 investment
    Stage 2Top applicants will be selected based on their potential to realise a new frontier in health and medical research and build a new industry ecosystem
    Successful Stage 2 applicants will receive up to 5 years of funding, ranging from $10 - $20 million per year

    The Frontier Health and Medical Research program will be overseen by an expert international panel and be consistent with the Australian Medical Research Innovation strategy.

    Seeking your input:

    At this stage we are canvassing colleagues across MACH to express interest. This is NOT a selection process. The value and purpose of this round is:

    • to help colleagues and groups to crystallise their ideas for the Frontiers program;
    • identify the major themes, synergies or overlaps;
    • to inform the MACH and institutional leadership of the kind of bids/support that may be required;
    • start canvassing support and partners where relevant.

    Please submit the completed forms to

    Projects and ideas received by Friday 29 June 2018 will be discussed at the July meeting of the MACH Research Platforms Committee.

  • Closed Funding Opportunities

    NHMRC Rare Cancers, Rare Diseases and Unmet Need Program: Low Survival Cancers and Diseases (LSCD) Grant Opportunity

    This competitive grant opportunity will provide support for publicly funded clinical trials that address low survival cancers and diseases.  Applications to this grant opportunity must propose a single clinical trial that aims to improve survival rates for Australians with a low survival cancer or other disease.

    The Australian Government has announced a total of up to $10 million from the MRFF for this grant opportunity. Grants of up to five years duration will be considered with funding anticipated to commence in July/August 2018. It it anticipated that up to seven grants will be funded.

    This scheme closed on 18th April 2018. Outcomes are expected in August 2018.


    BioMedTech Horizons Expressions of Interest – MTPConnect

    Expressions of Interest (EOIs) are open for the Australian Government's $5 million BioMedTech Horizons program, an initiative to support innovative collaborative health technologies that address key health challenges. MTPConnect is delivering this grant program on behalf of the Australian Government as part of the $20 billion Medical Research Future Fund.

    MTPConnect welcomes ideas that are set to customise and revolutionise healthcare, stimulate inter-disciplinary collaboration between research, industry and technology sectors, and foster strong entrepreneurship potential.

    Investments from the program will be focused on supporting cutting-edge ideas in precision medicine and 3D anatomical printing towards proof-of-concept and commercialisation. Innovative technologies in these areas can play a key role in significantly transforming the national healthcare system and promote Australia's international ranking as a leader in biotechnology and medical technology.

    Approximately $3 million is reserved for supporting ideas in precision medicine and $2 million for ideas in the 3D anatomical printing area. Up to $1 million is offered in funding for individual projects over the next two years, to drive innovation and foster commercialisation. Cash and/or in-kind contributions from the applicant will be viewed favourably.

    Stage 2 of this scheme closed on 15th January 2018.


  • Programs funded to date

    The MRFF provides medical research funding via partner agencies that run peer review funding programs. It is not possible to apply directly to the MRFF for funding. For example, the MRFF has already partnered with the NHMRC, CanTeen and The Cure for MND Foundation. The University of Melbourne regularly monitor programs announced by the MRFF to provide support for applicants as call for applications emerge. Details of available support and internal submission procedures will be posted on Research Professional

    First disbursements from the Medical Research Future Fund

  • Strategy and Priorities

    MRFF National Consultation -  SAVE THE DATE!

    A national consultation process to inform the development of the next iteration of the Australian Medical Research and Innovation Priorities 2018-2020 (MRFF Priorities) I about to commence. The MRFF is interested in hearing reflections on the first set of MRFF Priorities from people with an interest in ensuring the Priorities for 2018-2020 accurately reflect strategic research investment opportunities.

    The consultation will commence with the release of a ‘Priorities Consultation Discussion Paper’ on 29 June 2018, followed by a series of public forums and targeted themed roundtables in July and August 2018.

    The Melbourne Public forum will be held on 30 July, further information on venue and time will made available shortly through

    Australian Medical Research and Innovation Strategy 2016-2021
    Australian Medical Research and Innovation Priorities 2016-2018

  • More information and contacts

    Research Australia MRFF
    Department of Health MRFF

    For general enquiries and requests for coordinating information sessions, please contact:

    Manager (Health & Medical Grants), Major Initiatives, Contracts and Grants
    Frank Anastasopoulos
    +61 3 8344 8208
    +61 424 004 794