Predicting stem cell behaviour
Available for: Hons/MSc and undergraduate research projects.
Location: Centre for Stem Cell Systems and Melbourne Integrative Genomics, University of Melbourne
Project title: Predicting stem cell behaviour
Description: Mesenchymal stromal cells (MSC) are resident tissue cells that are increasingly used for treatment of inflammatory disorders. However the identity and function of these cells remains controversial. We recently published a computational tool that can predict the identity of MSC, and this project builds on this tool to find predictors of MSC function. The project is held jointly between the Centre for System Genomics and laboratory of Dr Kim-Anh Le Cao, and the Centre for Stem Cell Systems in the laboratory of Professor Christine Wells.
Suitable for: Maths-stats savvy students, interested in dimension reduction of large biological data sets and variable selection methodologies to find clinical predictors of cell function.