Statistical genetics with a particular interest in developing methods for, and applying them to, studies of population structure and immunogenetics
The Leslie lab work in the field of mathematical, statistical and population genetics. The group's main interests are in both applying mainstream statistical developments to genetics, and in developing new statistical methods motivated by problems arising in genetics. In particular, the team works on developing statistical methods for the analysis of modern genetic and genomic data sets, with a particular focus on understanding the role of genetics in human diseases. Within this broad field, there are two main interests. The first is developing statistical methods to type immune system genes (e.g. HLA) using SNP and other data. The second interest is in detecting and understanding population structure, and accounting for this in studies of disease and other phenotypes.