Melbourne Protein Characterisation

3 minute read

A woman behind an x-ray Diffractometer machine

The Melbourne Protein Characterisation platform offers technology for identifying the characteristics of individual proteins, including their size, structure and physiochemical properties.

The platform supports protein discovery research across a range of experiments and procedures. These include experiments to understand function and behaviour of molecular interaction and structural analyses.

We offer training and advice, and can help researchers with:

  • Peptide synthesis and protein production (for insect and mammal cells)
  • Studying molecular binding and interactions
  • Analysing oligomerisation and association states
  • Determining protein size, shape and secondary structure
  • Studying heterogeneity and aggregation
  • Analysing fluorescence and UV absorbance
  • Detecting small molecule binding
  • Analysing X-ray diffraction-based structure for small molecules and proteins.

Resources

Protein production

  • Peptide synthesizer

Protein interaction

  • Analytical ultracentrifuges
  • Isothermal titration calorimeters
  • Circular dichroism spectrometers
  • Dynamic light scattering - Zetasizer
  • Differential scanning calorimeter
  • Surface plasmon resonance - Biacore
  • 18 angles light scattering system

X-ray diffraction

  • X-ray diffractometer - Rigaku Synergy-S

User information

The platform is open access to all researchers for both academic and industry use. We offer training and fee-for-service options.

More information about the platform.

Image: Peter Casamento.

Contact us

Yan Hong Tan

yan.tan@unimelb.edu.au

Phone: +61 3 9035 3858

Access the booking system.

More information on this platform can be found on the Research Gateway, which is available to all University of Melbourne academic and honorary staff, graduate researchers and professional staff.  Please note, to access the Research Gateway, you will need to login with your University of Melbourne username and password.