Mass spectrometry

Generating a mass spectrum of all the different types and structures of molecules within a sample

Proteomics enquiries
Nicholas Williamson 
Email
nawill@unimelb.edu.au
Phone
+61 3 8344 2206
Metabolomics enquiries
Zofia Felton
Email
zfelton@unimelb.edu.au
Phone
+61 3 8344 4099

The Capability

Mass spectrometry is an analytical technology that is used in a variety of different fields of science and medicine to elucidate the chemical structure of molecules such as protein peptides or chemical compounds.  The sample material (like blood plasma or urine) is separated into its constituent molecules by ionisation; thereby generating a collection of charged molecules or fragments which are then measured for their mass-to-charge ratios. This generates a mass spectrum of all the different types and structures of molecules within the sample.

The University of Melbourne has specialist expertise in both Metabolomics and Proteomics areas of mass spectrometry. Proteomics refers to the mass spectrometry used to identify, characterise and quantify proteins within a given sample and involves separation and sequencing of the core protein structure as well as analysis of post-translational modifications. It has wide-reaching applications in science and medical research such as drug development and testing and biomarker discovery. Metabolomics measures the chemical processes involving metabolites; the end product of cellular processes that are indicative of changes within the cellular environment and are useful indicators of abnormalities/health, responses to drug testing and discovering new biomolecules.

* If you are a researcher working for an end-user organisation from industry or government, come and see the Melbourne node of Metabolomics Australia to discuss submitting an application for seed funding of up to $10,000 from Bioplatforms Australia for a collaborative project.