CBRI Seminar – Jonathan Keith – 17th June 2016

A seminar by Associate Professor Jonathan Keith (School of Mathematical Sciences, Monash University)

Detecting ncRNAs in the human genome using Bayesian multiple change-point models

Large numbers of currently unidentified functional ncRNAs, even whole classes of undiscovered elements, are likely to be encoded in the human and other genomes. In this talk I will discuss ~1000 putative new ncRNAs, most of which are located in the introns of transcription factors, that are conserved in the genomes of human, mouse and zebrafish. The methodology used to identify these elements involves Bayesian multiple change-point models used to segment alignments into classes with characteristic patterns of base composition, conservation level and mutational biases. These putative ncRNAs were detected as the result of joint work with Dr Robert Bryson-Richardson at Monash University.

When: 11am, Friday 17 June
Where: ESJ King Theatre
Level 3, Medical Building
University of Melbourne, Parkville
No registration required - ALL WELCOME. Please direct enquiries to Andrew Siebel.

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Andrew Siebel

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